People >> Sarah Behrens

Name: Dr. Sarah Behrens Status: Postdoc Email: s.behrensuni-muenster.de Room:  202 Tel:  +49-(0)251-83-21096

• Probabilistic models of DNA sequence evolution (e.g. Markov models)
• Evolution of transcriptional gene regulation
• Analysis of next generation sequencing data (e.g. ChIP-seq data)
• Word statistics and motif enrichment analysis
• Biostatistics in general

• since July 2010: Post Doc at the Institute for Evolution and Biodiversity, Evolutionary Bioinformatics Group, Prof. Erich Bornberg-Bauer; Scientific Coordinator of the DFG-SPP "Host Parasite Coevolution"
• Oct. 2008 - Jun. 2010: Post Doc at the Max Planck Institute for Molecular Genetics, Department of Computational Molecular Biology in the group of Prof. Martin Vingron
• Jun. 2008: PhD degree (Dr. rer. nat.) at the Faculty for Mathematics and Computer Science at the Westfälische Wilhelms-Universität Münster, Germany
  topic of the thesis: Identification of over- and underrepresented words in DNA sequences and a probabilistic analysis of the Longest Common Subsequence of two DNA sequences using large deviations theory (moderate deviations)
• Mar. 2006 - Sep. 2008: Research/Teaching Assistant and PhD studies in the group of Prof. Matthias Löwe at the Institute of Mathematical Statistics in Münster
• Dez. 2005: Diploma in Mathematics (minor subject: biology) at the Faculty for Mathematics in Münster
  
  topic of the thesis: Alignments of DNA and protein sequences; characterization of the length and composition of high scoring sequence pairs
• 2005: Internship at the Center of Advanced European Studies and Research (Bonn) in the group "Functional Peptides"
• 2002-2005: Student Assistant at the Faculty for Mathematics in Münster
• 2000-2005: Studies of Mathematics (and Biology) in Münster
• 2000: Abitur at the Städtisches Gymnasium Kamen, Germany

• Behrens, S., Nicaud, C., Nicodème, P.: An automaton approach for waiting times in DNA evolution.
  J. Comput. Biol., Vol. 19, Number 5, pp. 550-562, 2012. (article)


• Falconnet, M., Behrens, S.: Accurate estimations of evolutionary times in the context of strong CpG hypermutability. J. Comput. Biol., Vol. 19, Number 5, pp. 519-531, 2012. (article)


• Bucsenez, M., Rüping, B., Behrens, S., Twyman, R.M., Noll, G.A., Prüfer, D.: Multiple cis-regulatory elements are involved in the complex regulation of the sieve element-specific MtSEO-F1 promoter from Medicago truncatula, Plant Biology, doi: 10.1111/j.1438-8677.2011.00556.x, 2012. (article)


• Göke, J., Jung, M., Behrens, S., Chavez, L., O’Keeffe, S., Timmermann, B., Lehrach, H., Adjaye, J., Vingron, M.: Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development, PLoS Comput. Biol., vol. 7 (12) pp. e1002304, 2011. (article)


• Żemojtel, T. Kiełbasa, S.M., Arndt, P.F., Behrens, S., Bourque, G., Vingron, M.: CpG deamination creates transcription factor binding sites with high efficiency, Genome Biol. Evol., doi: 10.1093/gbe/evr107, 2011. (article)


• Behrens, S., Vingron, M.: Studying the evolution of promoters: a waiting time problem, J. Comput. Biol, Vol. 17, Number 12, pp. 1591-1606, 2010. (article)


• Behrens, S., Löwe, M.: Moderate deviations for word counts in biological sequences, Journal of Applied Probability, Vol. 46, No. 4, pp. 1020-1037, 2009. (article)


• Behrens, S., Moderate und große Abweichungen zur statistischen Analyse biologischer Sequenzen, PhD thesis, 2008. (German version)


• Behrens, S., Grenzwertsätze für empirische Funktionen von Partialsummen zur Untersuchung von DNA- und Proteinsequenzen, Diploma thesis, 2005. (German version)

• 5th International Workshop on Applied Probability, Madrid, 2010
  Invited Talk: Moderate deviations for word counts in biological sequences.
• 20th Annual MASAMB workshop, Warwick, UK, 2010
  Talk: Studying the evolution of promoter sequences: a waiting time problem.
• 6th Annual RECOMB Satellite on Regulatory Genomics, Boston, 2009
  Poster: Studying the evolution of promoter sequences: a waiting time problem.
• SSB Meeting, Laboratoire Statistique & Génome, Université d'Evry, 2009
  Invited Talk: Studying the evolution of promoter sequences: a waiting time problem.
• 33rd Conference on Stochastic Processes and Their Applications, Berlin, 2009
  Poster: Moderate deviations for word counts in biological sequences.