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Andrew D. Moore

People >> Andrew D. Moore

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Name: Andrew D. Moore
Status: Postdoc
Email: a.mooreuni-muenster.de
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Room:  100.20  
  Westphalian Wilhelms-University
Institute for Evolution and Biodiversity
Evolutionary Bioinformatics Group
Hüfferstrasse 1, D48149 Münster, Germany
Phone: +49-(0)251-83-21634
Fax:     +49-(0)251-83-24668 
Curriculum
  • since October 2011: Postdoctoral fellow
  • June 2007 - August 2011: Ph.D Student, Evolutionary Bioinformatics
  • June 2006 - May 2007: Diplom (equiv. MSc) in the group of Evolutionary Bioinformatics, IEB
  • 2004: Visiting student, Faculty of Science, University of British Columbia, Vancouver, Canada
  • 2001-2005: Studies in Biology and Computer Science, WWU Muenster

Awards
Teaching
  • Bioinformatics I (WS 08/09, WS 09/10, WS 10/11)
  • Advanced Programming for Bioinformatics (SS 09)
  • Supervision support of students at BSc and MSc level (07/08/09)

Research Interests
  • Modularity of protein evolution
    The linear order of domains that makes up a protein is referred to as a domain arrangement or a domain architecture. The analysis of protein domain arrangements across species indicates that functional novelty is achieved by the recombination of existing domains, as opposed to the invention of new domains, coining the concept of modular protein evolution. We study the evolution of proteomes by quantifying the nature and rates of modular re-arrangement events and the functional impact these events have.

  • Development of domain-centric tools for protein anaylsis


Tools / Software

  • AnGSTD
    Software for the analysis of modular, domain-wise anaylsis of proteins and proteomes. It is a Java re-write (and extension) of a software package written in Perl by January Weiner.

  • xdomsuite
    A Ruby API for the analyis of domain-wise evolution. Allows the creation of proteome objects, which contain Protein objects and domain objects. Each of these objects supports various opertaions frequently used in domain analysis.

  • RTree
    A simple Ruby API for the creation of a tree object that supports tree-traversal methods and association of objects with nodes.


Publications



Attended conferences & workshops; conference contributions

 
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